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  • Return to More On Orthopaedic Medicine > Individual Prolotherapy Study Summaries > Groin Pain

    Regenerative Injection of Elite Athletes With Career-Altering Chronic Groin Pain

    Topol GA, Reeves KD: Regenerative injection of elite athletes with career-altering chronic groin pain who fail conservative treatment: a consecutive case series. Am J Phys Med Rehabil 2008;87; .

    Dr. Reeves' Notes:   Dextrose 12.5% injection returns 66/72 elite rugby and soccer players to full sport who were prevented from high level play by chronic groin pain. This was a continuation of the consecutive patient study by Topol et al in 2005 with durability of benefit confirmed by up to 6 year followup.


    An abstract of this study on Regenerative Injection of Elite Athletes is available here, with a copy of the content below.

    Objective: To obtain multisport and long-term outcome data from the use of regenerative injection therapy on career-threatened athletes.

    Design: Consecutive enrollment of elite performance-limited athletes with chronic groin/abdominal pain who failed a conservative treatment trial. The treatment consisted of monthly injections of 12.5% dextrose in 0.5% lidocaine in abdominal and adductor attachments on the pubis. Injection of the nociceptive source was confirmed by repetition of resistive testing 5 mins after injection.

    Results: Seventy-five athletes were enrolled. Seventy-two athletes (39 rugby, 29 soccer, and 4 other) completed the minimum two-treatment protocol. Their data revealed a mean groin pain history of 11 (360) mos. Average number of treatments received was 3 (16). Individual paired t tests for Visual Analog Scale (VAS) of pain with sport (VAS Pain) and Nirschl pain phase scale measured at 0 and an average of 26 (673) mos indicated VAS Pain improvement of 82% (P <10 10 ). and Nirschl pain phase scale improvement of 78% (P <10 10 ). Six athletes did not improve following regenerative injection therapy treatment, and the remaining 66 returned to unrestricted sport. Return to unrestricted sport occurred in an average of 3 (15) mos.

    Conclusions: Athletes returned to full elite-level performance in a timely and sustainable manner after regenerative injection therapy using dextrose.


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